Cuddy: I ended it.
House: What?
Cuddy: I’m stuck, House. I keep wanting to move forward. I keep wanting to move on and I can’t. I mean, my new house with my new fiancé and all I can think about is you. I just need to know if you and I can work.
House: You think I can fix myself ?
Cuddy: I don’t know.
House: ‘Cause I’m the most screwed-up person in the world.
Cuddy: I know. I love you. I wish I didn’t. But I can’t help it.

6x21 'Help Me'